Abstract

BACKGROUND Oxidative stress is detrimental to semen quality and has a significant role in the etiology of malesubfertility. METHODS Dietary intake of antioxidants were compared between thirty two men with oligolastheno/ teratazoospermic(cases) and 32 normospermic volunteers (controls) attending fertility clinic in Mirza Koochak-khanHospital in Tehran, Iran. All participants were nonsmokers and matched according their age and Body MassIndex (BMI). Nutrient consumption was calculated using a semi- quantitative food frequency questionnaire.Semen samples were collected and were assessed by measuring volume, concentration, motility and morphology. RESULTS infertile subjects had a significantly lower intake of zinc and folate compare to control ones(p<0.001). Dietary intake of vitamin C and E was lower than recommended values in 59.4% of case group thatwas significantly different from control ones (p<0.05). In control group, 36.4 and 40.9% of participants had insufficientdietary intake of vitamin C and E, respectively. Significant correlations were found between folate(r=0.5, p<0.001), zinc (r=0.6, p<0.001) and percentage of motility and also between vitamin E and morphology(r=0.3, p=0.03), zinc and concentration (r=0.4, p=0.004) in all participants. CONCLUSION summary, a low intake of folate, zinc, and vitamin E were related to poor sperm concentrationand motility.