Abstract

Background: Breast cancer, one of the most prevalent cancers among women, can pose numerous psychological challenges for patients. In this context, the Quranic lifestyle, as a rich source of religious teachings, can play a significant role in promoting mental health and quality of life among patients. Methods: This cross-sectional analytical study was conducted on 85 breast cancer patients in the summer of 2023. A questionnaire with eight items in two dimensions was designed. Face validity was determined using the Item Impact Score (IIS), and content validity was assessed using the Content Validity Index (CVI) and Content Validity Ratio (CVR). Exploratory factor analysis was employed to categorize items and identify dimensions for evaluating construct validity. Cronbach's alpha coefficient was used to determine internal consistency and test-retest reliability was assessed using the Pearson correlation coefficient and Intraclass Correlation Coefficient (ICC). Findings: The mean (standard deviation) of participants age was 42.50 (11.58) years. The final version of the scale consisted of 8 items in 2 dimensions. The overall Cronbach's alpha was 0.94, and for each dimension, it was greater than 0.80. The confirmatory factor analysis results showed the appropriate fit of the latent variable model. Conclusion: The validity and reliability of the scale were confirmed in this study. Therefore, this 8-item scale is proposed as a suitable and efficient tool for measuring attitudes towards the Quran, hope, and quality of life in breast cancer patients undergoing radiotherapy. © 2025 Isfahan University of Medical Sciences(IUMS). All rights reserved.