Abstract

Background: Endometriosis is defined as the existence of endometrial glands and stroma outside the uterine cavity. This disease is responsible for about 15 of the indications for assisted reproductive technologies (ART). Materials and Methods: This study is a retrospective cross-sectional study on 1382 women aged 18-42 who underwent ART in Yazd Reproductive Sciences Institute during 2018-2022. Women were divided into two groups: women with endometriosis (N = 173) and women with a tubal factor or unexplained infertility as the control group (N = 1209). Chemical and clinical pregnancy rates and live birth rates were compared. Results: Women with endometriosis had significantly (P < 0.001) lower retrieved oocytes (7.73 +/- 5.52 vs 11.53 +/- 7.46), metaphase II oocytes (6.27 +/- 4.72 vs 9.37 +/- 6.62), and the total number of obtained embryos (3.95 +/- 3.52 vs 6.13 +/- 5.02). Chemical (P = 0.001) and clinical (P = 0.028) pregnancy rates were lower in women with endometriosis, while live birth rates showed no difference between the two groups (P = 0.069). Conclusion: The findings of this study showed that endometriosis can disturb reproductive outcomes after ART.