Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

The role of viruses in adenocarcinoma development

(2020) The role of viruses in adenocarcinoma development. Infection, Genetics and Evolution. ISSN 15671348 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Cancer is a leading public health issue that accounts for million deaths around the world every year. Human cancers contain over 100 types, which are categorized into different groups. Adenocarcinoma is one of those categories of cancer that begins from the glans and involves various tissues such as lung, esophagus, pancreas, prostate and colorectal. A range of risk factors has been identified for the development and progression of adenocarcinomas. One of these risk factors are viruses that serves special mechanisms to affect important host cell factors and tumorigenic pathways, contributing in development and promotion of adenocarcinomas. Here, we summarized the main viruses and their mechanisms implicated in the course of various adenocarcinomas development. © 2020 Elsevier B.V.

Item Type: Article
Keywords: Adenocarcinoma Neoplasm Viruses Animals Cell Transformation, Viral Disease Susceptibility Humans Risk Assessment Risk Factors beta catenin CXCL16 chemokine cyclin D1 cyclin dependent kinase inhibitor 2A epidermal growth factor receptor fibroblast growth factor 2 gelatinase B hypoxia inducible factor 1alpha immunoglobulin G interleukin 17 interleukin 6 interleukin 8 mitogen activated protein kinase Myc protein phosphatidylcholine phosphatidylinositol 3 kinase phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase platelet derived growth factor alpha receptor protein E6 protein E7 protein kinase B protein p53 retinoblastoma protein STAT3 protein transforming growth factor alpha vasculotropin Wnt protein angiogenesis BK virus cancer growth cancer risk carcinogenesis colorectal carcinoma Cytomegalovirus disease transmission DNA damage esophageal adenocarcinoma extracellular matrix Hepatitis B virus Hepatitis C virus human Human papillomavirus type 16 Human papillomavirus type 18 Human papillomavirus type 31 Human papillomavirus type 33 Human papillomavirus type 45 JC virus keratinocyte leukocyte count lung adenocarcinoma Merkel cell polyomavirus nonhuman pancreas adenocarcinoma priority journal prostate adenocarcinoma prostate hypertrophy protein expression Review signal transduction Th17 cell virus virus detection virus load Xenotropic murine leukemia virus Xenotropic murine leukemia virus related virus animal disease predisposition metabolism pathology risk factor virus cell transformation
Journal or Publication Title: Infection, Genetics and Evolution
Volume: 86
Identification Number: https://doi.org/10.1016/j.meegid.2020.104603
ISSN: 15671348 (ISSN)
Depositing User: Mr mahdi sharifi
URI: http://eprints.ssu.ac.ir/id/eprint/31737

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