Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Items where Author is "Khoobi, Mehdi"

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Number of items: 20.

(2019) 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease. Chemistry & biodiversity. e1800436. ISSN 1612-1880

(2019) Synthesis and biological evaluation of new N-benzylpyridinium-based benzoheterocycles as potential anti-Alzheimer's agents. Bioorganic chemistry. pp. 559-568. ISSN 1090-2120

(2018) Novel 3-phenylcoumarin-lipoic acid conjugates as multi-functional agents for potential treatment of Alzheimer's disease. Bioorganic chemistry. pp. 223-234. ISSN 1090-2120

(2018) Design, synthesis and evaluation of novel multi-target-directed ligands for treatment of Alzheimer's disease based on coumarin and lipoic acid scaffolds. European journal of medicinal chemistry. pp. 600-614. ISSN 1768-3254

(2017) New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease. European journal of medicinal chemistry. pp. 280-289. ISSN 1768-3254

(2017) Facile synthesis and antiproliferative activity of 7H-benzo7,8chromeno2,3-dpyrimidin-8-amines. European Journal of Medicinal Chemistry. pp. 128-136.

(2017) Metal-Chelate Immobilization of Lipase onto Polyethylenimine Coated MCM-41 for Apple Flavor Synthesis. Applied Biochemistry and Biotechnology. pp. 1-19.

(2017) Synthesis and anti-acetylcholinesterase activity of N-(indolyl)ethyl)- coumarin-yloxy)alkanamides. Journal of Chemical Research. pp. 120-123.

(2017) Synthesis of novel benzimidazole and benzothiazole derivatives bearing a 1,2,3-triazole ring system and their acetylcholinesterase inhibitory activity. Journal of Chemical Research. pp. 30-35.

(2016) Synthesis and structure-activity relationship study of tacrine-based pyrano[2,3-c]pyrazoles targeting AChE/BuChE and 15-LOX. European journal of medicinal chemistry. pp. 298-308. ISSN 1768-3254

(2016) Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety. European Journal of Medicinal Chemistry. pp. 40-46.

(2015) Synthesis and anticholinergic activity of 4-hydroxycoumarin derivatives containing substituted benzyl-1,2,3-triazole moiety. Chemical biology & drug design. pp. 1215-20. ISSN 1747-0285

(2015) 9H-Carbazole Derivatives Containing the N-Benzyl-1,2,3-triazole Moiety as New Acetylcholinesterase Inhibitors. Archiv der Pharmazie. pp. 366-374.

(2015) Anticonvulsant activity of 1,2,4-triazine derivatives with pyridyl side chain: Synthesis, biological, and computational study. Medicinal Chemistry Research. pp. 2505-2513.

(2015) New tetracyclic tacrine analogs containing pyrano2,3-cpyrazole: Efficient synthesis, biological assessment and docking simulation study. European Journal of Medicinal Chemistry. pp. 296-303.

(2015) Synthesis and biological evaluation of 5-benzylidenerhodanine-3-acetic acid derivatives as AChE and 15-LOX inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. pp. 389-395.

(2014) Synthesis and anti-cholinesterase activity of new 7-hydroxycoumarin derivatives. European journal of medicinal chemistry. pp. 536-44. ISSN 1768-3254

(2014) Indolinone-based acetylcholinesterase inhibitors: Synthesis, biological activity and molecular modeling. European Journal of Medicinal Chemistry. pp. 375-381.

(2013) Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors. European Journal of Medicinal Chemistry. pp. 252-259.

(2013) Synthesis of some new 3-coumaranone and coumarin derivatives as dual inhibitors of acetyl- and butyrylcholinesterase. Archiv der Pharmazie. pp. 577-587.

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