Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Synthesis and biological evaluation of 1,3,4,5-tetrasubstituted pyrazole derivatives

(2016) Synthesis and biological evaluation of 1,3,4,5-tetrasubstituted pyrazole derivatives. Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences. pp. 973-977.

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

We report a solvent-free synthesis of novel 1,3,4,5-tetrasubstituted pyrazoles and investigate their inhibitory activity against soybean 15-lipoxygenase. It was revealed that all synthesized compounds exhibited good activity, and among them, 3-(furan-2-yl)-1,4,5-triphenyl-1H-pyrazole (5j) showed 10 times stronger inhibitory activity in comparison to the reference drug quercetin. © 2016, Verlag der Zeitschrift fur Naturforschung. All rights reserved.

Item Type: Article
Page Range: pp. 973-977
Journal or Publication Title: Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences
Volume: 71
Number: 9
Publisher: Verlag der Zeitschrift fur Naturforschung
Depositing User: ms soheila Bazm
URI: http://eprints.ssu.ac.ir/id/eprint/9994

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