Abstract

Kindler syndrome is a rare autosomal recessive condition, characterized by multiple skin and mucosal abnormalities. Among the latter, esophageal involvement is an infrequent manifestation which may be completely asymptomatic or complicate with dysphagia. We report two sisters presenting with cutaneous features and severe dysphagia. Endoscopic examination showed that the patients were affected with a rare condition named esophageal web. Both patients showed much improvement after balloon dilation. Clinicians should be aware of the potential disease complications and balloon dilation approach should be considered as primary therapy in the Kindler syndrome patients with esophageal web.