Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Pediatric kidney transplant with laparoscopic donor nephrectomy

(2014) Pediatric kidney transplant with laparoscopic donor nephrectomy. Experimental and Clinical Transplantation. pp. 391-395.

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Abstract

Objectives: To evaluate outcomes and complications with pediatric living-donor kidney transplant, mostly performed with laparoscopic donor nephrectomy. Materials and Methods: In the 25 years between February 1987 and December 2012, there were 493 children aged � 17 years who received a kidney transplant. Demographic characteristics, graft and patient survival, rejection episodes, and complications were recorded. Analysis was performed for 3 sequential periods (1987-1994, 1995-2002, and 2003- 2012). Results: The mean patient age was 13 ± 4 years (age range, 2.5-17 y). There were 290 males (59). Glomerulonephritis was the most common cause of end-stage renal disease. Preemptive kidney transplant was performed in 412 patients (84). Donor nephrectomy was performed laparoscopically in 445 patients (90). The 5-year graft and patient survival were improved from 1987-1994 to 2003-2012. The overall death-censored graft survival was 96 at 1 year, 78 at 5 years, and 66 at 10 years after transplant. The overall patient survival was 96 at 1 year, 83 at 5 years, and 75 at 10 years after transplant. Conclusions: Kidney transplant is available for most pediatric patients and has acceptable graft and patient survivals. Laparoscopic donor nephrectomy improves donor satisfaction and morbidity, and may provide excellent graft outcomes in children. © Ba�kent University 2014 Printed in Turkey. All Rights Reserved.

Item Type: Article
Keywords: azathioprine; cyclosporin; mycophenolic acid 2 morpholinoethyl ester; prednisone; immunosuppressive agent, acute graft rejection; adolescent; Article; causal attribution; child; clinical evaluation; delayed graft function; demography; end stage renal disease; female; follow up; glomerulonephritis; graft survival; human; kidney graft; kidney graft rejection; laparoscopic surgery; living donor; major clinical study; male; nephrectomy; outcome assessment; pediatric surgery; preschool child; school child; survival rate; trend study; adverse effects; age; graft rejection; Kaplan Meier method; Kidney Failure, Chronic; kidney transplantation; laparoscopy; living donor; mortality; nephrectomy; procedures; register; retrospective study; risk factor; time; treatment outcome, Adolescent; Age Factors; Child; Child, Preschool; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Failure, Chronic; Kidney Transplantation; Laparoscopy; Living Donors; Male; Nephrectomy; Registries; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome
Page Range: pp. 391-395
Journal or Publication Title: Experimental and Clinical Transplantation
Volume: 12
Number: 5
Publisher: Baskent University
Depositing User: ms soheila Bazm
URI: http://eprints.ssu.ac.ir/id/eprint/9183

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