Abstract

Preeclampsia is a heterogeneous disorder with variable maternal and fetal manifestations. Several studies have been performed to assess the validity of uterine artery. Doppler examination screening tool for pre-eclampsia. The purpose of this study was to evaluate the predictive value of Doppler investigations of the uterine circulations during 14-16 weeks of gestation with regard to the development of preeclampsia and/or IUGR in study population. This prospective observational study was carried out at university hospital. All 456 pregnant women referred to hospital from October 2011 to october2012, ultrasound sonography was done at 14-16 weeks of gestation. In all Doppler measurements, the mean peak systolic (S) to end-diastolic (D) ratio of 3-5 cardiac cycle was computed by electronic capilers and the RI calculated as (S-D/S). A total of 456 pregnant women with mean age of 26.8±5.3 years were recruited during the study. The uterine artery RI at 14-16 weeks was significantly higher in 27 women subsequently developed preeclampsia (mean RI=0.7526±0.039) than in 429 pregnancy with a normal outcomes (mean RI=0.6440±0.059, P=0.001).The uterine artery RI also was significantly higher in 36 women developed IUGR (RI=0.7244±0.04730) compared with 420 women withnormal pregnancies (RI=0.6505±0.06043, P=0.001). Conclusion: RI=0.69 to predict preeclampsia and RI=o.7 to predict IUGR as mentioned are optional cut-off value for RI of the uterine artery in our study which are congruent with other studies. © IDOSI Publications, 2013.