Abstract

Objective: Patent ductus arteriosus (PDA) is one of the most congenital heart diseases. Closure is recommended because of the risk of infective endocardis, morbidity and mortality in the long term. The aim of this study was to assess the long term results of the transcatheter closure of PDA in infants using Amplatzer duct occlude (ADO). Methods: From May 2004 to September 2011, forty eight infants underwent transcatheter closure of patent ductus arteriosus. A lateral or right anterior oblique view aortogram was done to locate PDA and to measure its size. Before release of ADO, repeat aortogram was performed to evaluate for residual shunt and to confirm the appropriate deployment of the ADO. Follow up evaluations were done with transthoracic echocardiography at discharge, 1 month, 6 month, 12 month and yearly therefore Findings: The mean age of patients at procedure was 9.18±2.32 (range 3 to 12 month), mean weight was 6.73±1.16kg (range 4.5 to 10.1 kg). The devices were deployed successfully and occluded the PDA completely in 20 out of the 48 patients immediately after procedure. Twenty four patients had trivial or mild shunt and two patients had moderate residual shunt which disappeared in one patient within 24 hours and other patient with moderate shunt in 1 month. One patient (age 8 months) had mild LPA stenosis. The device emobolization occurred in two patients, immediately after the procedure in one patient and during night in other patient Conclusion: The long term results suggested that transcatheter closure of PDA using Amplatzer duct occluder is a safe and effective treatment in infants less than 1 year of age with minimal complications. © 2013 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, All rights reserved.