Abstract

Because of their desirable characteristics, ceramic-based scaffolds have emerged as prominent candidates for artificial bone replacements in bone regeneration procedures. Bredigite (Ca7MgSi4O16) ceramic has demonstrated favorable bioactivity, bone growth, and mechanical qualities, making it a viable candidate for replacing bone defects. This review presents the main techniques employed for the synthesis of bredigite. It was also mentioned how combining bredigite ceramic with other materials might increase the quality of composites. Because of the presence of magnesium in bredigite, it has higher mechanical properties and chemical stability than calcium silicates such as wollastonite, dicalcium silicate, and tricalcium silicate. The density and elastic modulus of bredigite is 3.4 gr/cm3 and 43 GPa, respectively. Higher mechanical properties of bredigite compared to polymers, and its biocompatibility, bioactivity, and osteoconductivity, can cause to higher quality of polymer-bredigite composite than that of polymer. Based on findings derived from many investigations conducted in in-vitro and in-vivo contexts, bredigite has great promise as a flexible and efficient material for bone tissue engineering. Additional research is needed to maximize the clinical applications of bredigite bioceramics. © The Author(s), under exclusive licence to Springer Nature B.V. 2024.