Abstract

AIM: To evaluate the effects of Garsin (garlic extract from Goldarou Company, Iran), on serum lipids and blood glucose in patients with type 2 diabetes mellitus. METHODOLOGY: A total of 45 hyperlipidemic type 2 diabetes cases were selected randomly from diabetics attending Yazd Diabetes Research Center. They underwent treatment with one Garsin tablet (300 mg of effective extract of garlic) three times a day for 4 weeks, and their serum lipids and blood glucose levels were measured both at the beginning and end of the study. RESULTS: Garsin significantly reduced total serum cholesterol by 18.6 mg/dl and serum LDL by 15.7 mg/dl ( P = 0.004, P = 0.001 respectively). The effects of Garsin tablet in lowering LDL ( P = 0.015) and increasing HDL ( P = 0.056) was more obvious in women than in men. CONCLUSIONS: Garsin is effective in lowering blood glucose and lipids and may be useful for treatment of diabetic and hyperlipidemic patients.