Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Vitamin C concentration of aqueous humor in senile cataract

(2005) Vitamin C concentration of aqueous humor in senile cataract. Journal of Research in Medical Sciences. pp. 269-273. ISSN 17351995 (ISSN)

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Abstract

Background: Oxidative agents like ultraviolet are one of the important cause of cataract and vitamin C is an important water soluble antioxidant agent in the aqueous humor. This study aimed to evaluate the concentration of vitamin C in the aqueous and plasma of patients with senile cataract. Methods: In a descriptive cross- sectional study on 85 patients (41 men and 44 women) admitted for cataratt surgery, aqueous (0.2 ml) and blood (5ml) were sampled just before operation under general anesthesia from anterior chamber and vein, respectively. Spectrophotometer measured the concentration of vitamin C in both samples. Results: The mean age was 64.3±11.1 years. Aqueous and plasma concentration of vitamin C was 4.29±1.11 mg/dl and 0.77±0.0332 mg/dl, respectively. The differences were statistical significant (P□0). Vitamin C of aqueous were equal in both sexes, but vitamin C of plasma in women were higher than men (P= 0.043). The concentration of vitamin C showed no relation to the type of cataract. Conclusions: Vitamin C of aqueous and plasma in senile cataract are lower than normal. More study is recommended for evaluating preventive effect of high vitamin C diets or supplements.

Item Type: Article
Keywords: Aqueous Plasma Senile cataract Vitamin C ascorbic acid adult aged anterior eye chamber aqueous humor article blood sampling cataract extraction concentration (parameters) controlled study diet supplementation drug blood level drug mechanism female general anesthesia hospital admission human major clinical study male sex difference spectrophotometry statistical significance
Page Range: pp. 269-273
Journal or Publication Title: Journal of Research in Medical Sciences
Volume: 10
Number: 5
ISSN: 17351995 (ISSN)
Depositing User: Mr mahdi sharifi
URI: http://eprints.ssu.ac.ir/id/eprint/32813

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