Abstract

• Aim: To investigate clinical presentation, classification, diagnosis, pathogenesis, complication and treatment of blepharitis. • Methods: In this study, 300 patients referred to general eye clinic have been chosen with diagnosis of blepharitis by Haag-streit slit-lamp examination. A questionnaire was filled in for patient with blepharitis. Then, the treatment of out-patient cases based on the causes of the condition was started. Patients we followed up and evaluated with respect to the results and complications of the treatment. • Results: The most common form of lesion in seborrheic dermatitis was squamous (62.5) but ulcerative lesions was the most common in infectious and mixed types (P <0.001). Also, Seborrheic blepharitis mostly had chronic clinical course but infectious type commonly was acute (P <0.001). A significant difference was found between the cause of blepharitis and incidence of complications including hordeolum, chalazia, epithelial keratitis, conjunctivitis, dry eye (P <0.05). Moreover, There was a significant difference between clinical course of disease and complications such as dry eye and epithelial keratitis (P <0.05). There was a close relationship between the underlying diseases including seborrheic dermatitis, atopic dermatitis, diabetes mellitus, allergy, acne rosacea and the cause of blepharitis(P <0.05). • Conclusion: The blepharitis is one of the most common problems in general ophthalmology and needs attention to prevent the complications.