Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

The prevalence of congenital malformations and its correlation with consanguineous marriages

(2010) The prevalence of congenital malformations and its correlation with consanguineous marriages. Oman Medical Journal. pp. 37-40. ISSN 1999768X (ISSN)

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Abstract

Objectives: Consanguinity has been a long standing social habit among some Iranians. This study is aimed at determining the role of consanguinity on congenital malformations and the correlation of inbreeding coefficient with anomalies. Methods: In this cross-sectional study, all the newborns who were born during 9 months period from April to December 2008. (n=1195) at Shahid Sadoughi hospital, Yazd, Iran were studied. Results: From 1195 neonates, 300 (25) were from consanguineous marriages and 895 (75) were from non-familial marriages. From 45 cases with anomalies, 34 (2.8) cases were from familial marriages, while only 11 (0.9 ) cases were from non-familial marriages. There was a significant correlation between parental marriages and the prevalence of anomaly (p=0.018). Conclusion: The prevalence of congenital anomalies was mostly observed in consanguineous marriages compared to non consanguineous marriages. © 2010, Oman Medical Specialty Board. All rights reserved.

Item Type: Article
Keywords: air pollution Apgar score Article awareness cesarean section congenital malformation consanguineous marriage consanguinity cross-sectional study education female genetic counseling gestational age human Iran major clinical study male maternal age newborn paternal age pregnancy outcome prenatal care prevalence questionnaire seasonal variation stillbirth vaginal delivery
Page Range: pp. 37-40
Journal or Publication Title: Oman Medical Journal
Volume: 25
Number: 1
Identification Number: https://doi.org/10.5001/omj.2010.9
ISSN: 1999768X (ISSN)
Depositing User: Mr mahdi sharifi
URI: http://eprints.ssu.ac.ir/id/eprint/32739

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