Abstract

AIM: To describe the involvement in relatives of keratoconus (KCN) patients with corneal topography map. METHODS: A total of 150 siblings of 300 eyes of 75 KCN patients referred to corneal clinic were studied and experienced complete slit-lamp, refraction examinations and topographic cornea maps provided by videophotokeratography. ANOVA, Fisher exact and Chi-square tests performed to compare of results. RESULTS: Of 150 siblings, 56 were female and 44 were male with average age of 21 (range 15-39) years. KCN and suspect KCN diagnosed in 12.3and 6.6respectively. The central keratometry (CK) was 46.5± 4.51 dioptr (D) in KCN and 45.66 ± 1.52D in suspect KCN. Inferior-superior value (I-S) was 3.51 ± 2.5D in KCN and 1.56 ± 1.22D in suspect KCN. In KCN condition the oval pattern was 67.6 (n = 25) and Round pattern detected 32.4 (n =12). In suspect KCN these patterns detected 90 and 10 respectively. Refractive errors in KCN were -7.5 to +1.25 dioptr (-1.25± 1.83), in suspect KCN 0.45 to -4.2 dioptr (-0.68± 0.76) and in healthy group 2.75 to -7.5 dioptr (-0.6± 1.12). Astigmatism was mild in 22.7, moderate and sever astigmatismin 18.3in KCN and suspect KCN CONCLUSION: Increasing KCN condition in healthy siblings of KCN patients shows require to screening plan to early diagnose and cautionly treatment of contact lens in these individuals.