(2018) Rituximab therapy in pulmonary alveolar proteinosis: A rare case report. Journal of Clinical and Diagnostic Research. OD07-OD08. ISSN 2249782X (ISSN)
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Abstract
Pulmonary Alveolar Proteinosis (PAP) is a rare disorder characterised by accumulation of surfactant in alveoli due to impaired surfactant clearance. Although, whole lung lavage is the standard treatment of PAP, rituximab has also been introduced as a therapeutic option for PAP. A 49-year-old female patient, a known case of PAP, came to the outpatient clinic complaining of exacerbation of dyspnoea. The patient was treated with rituximab four times in a year. Finally, the clinical status and spirometry tests showed improvement. Although, the main treatment for PAP is whole lung lavage, other therapeutic options may be useful too. According to the prior case reports and the present one, rituximab can be useful in treatment of PAP. © 2018, Journal of Clinical and Diagnostic Research. All rights reserved.
| Item Type: | Article |
|---|---|
| Keywords: | Anti-CD20 monoclonal antibody Ground glass opacity Surfactant chlorpheniramine hydrocortisone paracetamol rituximab adult Article case report clinical article computer assisted tomography dyspnea female forced expiratory volume forced vital capacity human iron deficiency anemia lung alveolus proteinosis lung lavage lung parenchyma middle aged oxygen saturation spirometry thorax radiography |
| Page Range: | OD07-OD08 |
| Journal or Publication Title: | Journal of Clinical and Diagnostic Research |
| Volume: | 12 |
| Number: | 4 |
| Identification Number: | https://doi.org/10.7860/JCDR/2018/32371.11419 |
| ISSN: | 2249782X (ISSN) |
| Depositing User: | Mr mahdi sharifi |
| URI: | http://eprints.ssu.ac.ir/id/eprint/32134 |
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