Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

A comparison of dual triggering (by administration of GnRH agonist plus HCG) versus HCG alone in poor ovarian responders in ART outcomes

(2018) A comparison of dual triggering (by administration of GnRH agonist plus HCG) versus HCG alone in poor ovarian responders in ART outcomes. Middle East Fertility Society Journal. pp. 350-353. ISSN 11105690 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: The use of dual triggering in high and normal responders accompanied with better IVF cycles outcomes. Also, it has been suggested that dual triggering in poor responders can accompanied with better results. Objective: The aim of present study was to evaluate whether the Dual trigger, can improve oocyte maturation in poor responder patients based on Bologna criteria and their ART outcomes. Materials and methods: All poor ovarian responder's patients underwent GnRH antagonist controlled ovarian hyperstimulation protocols in ART cycles. The participants' randomizations were done and patients divided into two groups. In the first group, final oocyte maturation was done by 6500 I.U.HCG alone. In the second group triggering was done with coadministration of 6500 I.U.HCG plus 0.2 mg triptorelin simultaneous (dual trigger). Oocytes retrieval was performed 36 h after triggering through transvaginal ultrasound guided. Routine IVF/ICSI was performed as appropriate. Results: Number of retrieved oocytes, number of mature oocytes (MII), number of fertilized oocytes (2PN), number of embryos formation, number of transferred embryos and embryos quality have not significant differences between two groups (p > 0.05). Also, fertilization and implantation rate, chemical and clinical pregnancy did not differ between groups. Conclusion: Dual triggering for final oocyte maturation in poor ovarian responders did not improve the number of mature oocytes (MII) and other ART cycle results. © 2018 Middle East Fertility Society

Item Type: Article
Keywords: Antagonist protocol Dual triggering Poor ovarian responders cetrorelix chorionic gonadotropin progesterone recombinant follitropin triptorelin adult Article combination drug therapy controlled study embryo embryo development embryo transfer female human human cell in vitro fertilization infertility therapy intracytoplasmic sperm injection major clinical study monotherapy oocyte maturation oocyte retrieval outcome assessment ovary hyperstimulation pregnancy randomized controlled trial transvaginal echography treatment response
Page Range: pp. 350-353
Journal or Publication Title: Middle East Fertility Society Journal
Volume: 23
Number: 4
Identification Number: https://doi.org/10.1016/j.mefs.2018.04.011
ISSN: 11105690 (ISSN)
Depositing User: Mr mahdi sharifi
URI: http://eprints.ssu.ac.ir/id/eprint/32071

Actions (login required)

View Item View Item