Abstract

Objective: The present study was aimed to investigation the effect of human chorionic gonadotropin (hCG) administration on the implantation and pregnancy outcomes in the frozen-thawed embryo transfer (FET) cycles. Design: This is a cross sectional retrospective study. Setting: Research and Clinical Center for Infertility of Yazd. Materials and methods: Totally, 200 FET cycles categorized into two groups: (A) hCG treatment group (N = 100), the patients received 3 doses of hCG after embryo transfer (ET); and (B) control group (N = 100), the patients received routine protocol. Finally, chemical and clinical pregnancy, and also implantation rates were compared between two groups. Results: All the cycles into two groups were matched regarding to demographic and basic characteristics. Moreover, there were significant differences between groups regarding chemical pregnancy (P = 0.048), clinical pregnancy (P = 0.041). There was a trend towards decrease of miscarriage rate in hCG treatment group, although differences were not significant (P = 0.434). Conclusion: Findings revealed an improvement in pregnancy rates following hCG administration in FET cycles. © 2018 Middle East Fertility Society