Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Putative Therapeutic Impact of Inflammasome Inhibitors against COVID-19-Induced ARDS

(2023) Putative Therapeutic Impact of Inflammasome Inhibitors against COVID-19-Induced ARDS. Current medicinal chemistry. pp. 1406-1419. ISSN 0929-8673

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Abstract

Given the importance of COVID-19-induced ARDS, recently, researchers have strived to determine underlying mechanisms involved in the inflammatory responses. In this regard, inflammasomes possess a distinct priority for cytokine storm occurrence and, subsequently, ARDS progression in ill patients with SARS-CoV-2 infection. In this mini-review, the characteristics of known inflammasome inhibitors and designed research in this field were concretely deciphered.

Item Type: Article
Keywords: ARDS COVID-19 inflammasome inhibitors NLRP3 SARS-CoV-2 acute lung injury nlrp3 inflammasome cytokine storm double-blind melatonin activation colchicine cells prevention relevance Biochemistry & Molecular Biology Pharmacology & Pharmacy
Page Range: pp. 1406-1419
Journal or Publication Title: Current medicinal chemistry
Journal Index: WoS
Volume: 30
Number: 12
Identification Number: https://doi.org/10.2174/0929867329666220906111550
ISSN: 0929-8673
Depositing User: Mr mahdi sharifi
URI: http://eprints.ssu.ac.ir/id/eprint/30572

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