(2018) Synthesis and biological evaluation of chalcone-triazole hybrid derivatives as 15-LOX inhibitors. Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences. pp. 77-83. ISSN 0932-0776
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Abstract
An efficient aldol condensation/click reaction sequence is employed for the synthesis of chalcone-triazole-based derivatives in moderate to good yields. The ability of target compounds to inhibit 15-lipoxygenase enzyme was investigated and moderate to low inhibitory activities were observed for the synthesized compounds.
| Item Type: | Article |
|---|---|
| Keywords: | chalcone lipoxygenase quercetine triazole molecular docking design 1,2,3-triazole anticancer analogs Chemistry |
| Page Range: | pp. 77-83 |
| Journal or Publication Title: | Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences |
| Journal Index: | WoS |
| Volume: | 73 |
| Number: | 2 |
| Identification Number: | https://doi.org/10.1515/znb-2017-0115 |
| ISSN: | 0932-0776 |
| Depositing User: | Mr mahdi sharifi |
| URI: | http://eprints.ssu.ac.ir/id/eprint/30308 |
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