Abstract

Objective: This study evaluated the effect of age on ovarian response to gonadotropin stimulation and the success of IVF & ICSI cycles. Methodology: In this retrospective analytic study, 280 women undergoing first IVF & ICSI cycles were collected. Patients were divided in three groups: <35 years old, 35 - 39 years and e"40 years old. Stimulation protocol for all. patients was tong standard protocol. Results: There were significant decrease in the number of follicles, oocytes retrieved and embryos obtained with increasing age (p<0.05). Fertilization rate did not differ significantly with increasing age (P>0.05). Clinical pregnancy rate were 21.8 in patients < 35, 13.2 in patients 35-39 and 5.9 in e"40 (p=0.157) and live birth rate were 14.2 in patients < 35, 7.9 in 35-39 and 5.9 in e"40 years old. (p=0.50) Conclusions: Clinical pregnancy rate & live birth rate diminished with increasing age.