Repository of Research and Investigative Information

Repository of Research and Investigative Information

Shahid Sadoughi University of Medical Sciences

Best insights on target molecules for drug design of nCOVID-19 based on pharmacological and peptide-based therapeutics

(2022) Best insights on target molecules for drug design of nCOVID-19 based on pharmacological and peptide-based therapeutics. Health Biotechnology and Biopharma. pp. 62-81.

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Abstract

Coronavirus is a non-segmented virus related to Coronaviridae family with an envelope and RNA that has a huge positive-sense single-stranded genome. The causative agent of COVID-19, severe acute respiratory coronavirus syndrome-2 (SARS-CoV-2) first appeared in China in 2019. The role of these viruses in pneumonia has greatly improved through molecular techniques. The virus structural proteins, viral replication factors, viral endocytosis process and enzymes are the key targets for designing drugs against COVID-19. This review considered the main molecular and cellular targets as well as peptide-based and pharmaceutical treatments for COVID-19 aiming for a better design of drugs against viruses with the best insights on key factors in this infection. Copyright © 2022, Health Biotechnology and Biopharma. All rights reserved.

Item Type: Article
Page Range: pp. 62-81
Journal or Publication Title: Health Biotechnology and Biopharma
Volume: 6
Number: 1
Publisher: Health Biotechnology And Biopharma
Depositing User: ms soheila Bazm
URI: http://eprints.ssu.ac.ir/id/eprint/13036

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