(2022) Clinical and Paraclinical Predictive Factors for In-hospital Mortality in Adult Patients with COVID-19: A Cross-sectional Study in Iran. Current Respiratory Medicine Reviews. pp. 142-151.
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Abstract
Background: COVID-19, a type of coronavirus emerged in Wuhan, China in December 2019, causing an epidemic of pneumonia with unknown reasons. Objective: This study aimed to investigate the factors affecting in-hospital mortality of patients with COVID-19 hospitalized in one of the main hospitals in central Iran. Methods: This retrospective cross-sectional study (February-May 2020) was conducted on patients with a confirmed diagnosis of COVID-19 admitted to Yazd Shahid Sadoughi Hospital in Iran. The patients with uncompleted or missed medical files were excluded from the study. Data were extracted from the patients' medical files and then analyzed. The patients were categorized as survivors and non-survivors groups, and they were compared. Results: Total 573 patients were enrolled and 356 (62.2) were male. The mean±SD of age was 56.29±17.53 years, and 93 (16.23) died. All the complications were more in non-survivors. Intensive care unit (ICU) admission was in 20.5 of the patients, which was more in non-survivors (P<0.001). The results of multivariate logistic regression test showed that pleural effusion in lung computed tomography (CT) scan (OR=0.055, P=0.019), white blood cell (WBC) (OR=1.418, P=0.022), serum albumin (OR=0.009, P<0.001), non-invasive mechanical ventilation (OR=34.351, P<0.001), and acute respiratory distress syndrome (ARDS) (OR=66.039, P=0.003) were the predictive factors for in-hospital mortality. Conclusion: In-hospital mortality with COVID-19 was about 16. Plural effusion in lung CT scan, increased WBC count, lower mount of serum albumin, non-invasive mechanical ventilation, and ARDS were obtained as the predictive factors for in-hospital mortality. © 2022 Bentham Science Publishers.
| Item Type: | Article |
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| Keywords: | aspartate aminotransferase; C reactive protein; corticosteroid; creatine kinase; hydroxychloroquine; lactate dehydrogenase; levofloxacin; lopinavir; meropenem; oseltamivir; phosphorus; ritonavir; serum albumin; troponin; urea, acidosis; acquired immune deficiency syndrome; acute kidney failure; adult; adult respiratory distress syndrome; albumin blood level; Article; artificial ventilation; blood clotting disorder; body temperature; breathing rate; calcium blood level; chronic kidney failure; chronic obstructive lung disease; clinical factor; computer assisted tomography; consciousness; coronavirus disease 2019; coughing; cross-sectional study; data analysis; diabetes mellitus; dyspnea; erythrocyte sedimentation rate; female; fever; Glasgow coma scale; glucose blood level; heart disease; heart failure; heart injury; hospital readmission; hospitalization; human; hypertension; in-hospital mortality; infection; intensive care unit; laboratory test; leukocyte; lung infiltrate; lymphadenopathy; major clinical study; male; myalgia; outcome assessment; oxygen saturation; paraclinical predictive factor; parameters; pleura effusion; polymerase chain reaction; potassium blood level; pulse rate; renal replacement therapy; respiratory failure; retrospective study; sepsis; septic shock; sodium blood level; systolic blood pressure; urea nitrogen blood level |
| Page Range: | pp. 142-151 |
| Journal or Publication Title: | Current Respiratory Medicine Reviews |
| Volume: | 18 |
| Number: | 2 |
| Publisher: | Bentham Science Publishers |
| Depositing User: | ms soheila Bazm |
| URI: | http://eprints.ssu.ac.ir/id/eprint/12835 |
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