Abstract

yslipidemia is a crucial risk factor for atherosclerosis (Walstra et al., 2005), and an abnormal metabolic condition characterized by disorders in lipid profile (Ference et al., 2019, Rosenson et al., 2011). Dyslipidemia is a critical yet controllable risk factor in coronary vascular disease (CVD) which cause deaths (Afshin et al., 2019). Antioxidant activity of sumac fruits against lipid peroxidation and free radicals was reported previously (Pourahmad et al., 2010). These findings indicated that sumac fruit extract might prevent the development of atherosclerosis. Also, its cardioprotective and hepatoprotective activities will benefit hypercholesterolemic conditions. The bioactive component(s) responsible for the lipidlowering effect of sumac fruits is not currently identified. Fruit extract decreased high serum lipid concentrations, alleviated abnormally elevated cardiac lipid levels, and modulated some enzyme indices and microscopic changes in the hypercholesterolemic conditions. Various parts of sumac contain a wide variety of medicinally remarkable phytochemical components previously (Ardalani et al., 2016, Pourahmad et al., 2010). Antioxidant properties can be achieved from high amounts of water-soluble tannins in sumac (Beretta et al., 2009). Sumac may reduce cardiovascular risk factors in patients with mild-to-moderate dyslipidemia. In a clinical trial, the participants with dyslipidemia indicated significantly diminished in Body Mass Index (BMI) and total cholesterol (TC) levels (Saberi-Karimian et al., 2020). Impacts of sumac on dyslipidemia included antioxidant effects and free radical cleaning against lipid peroxidation as the initial stage of atherosclerosis (Rayne and Mazza, 2007). Nowadays, several studies have underlined the function of herbs in the treatment of a sort of disorders, particularly the cardiovascular system (Al Mofleh, 2010). Sumac has © 2022,Journal of Nutrition and Food Security. All Rights Reserved.