Abstract

Introduction: The purpose of this study was to describe the clinicopathologic features of lip lesions for early diagnosis and suitable treatment of  patients. Methods: This was a  descriptive cross-sectional study on158 patients with lip lesions whose information was recorded in the Department of Pathology of Shahid Sadoughi Hospital from 2008-2012. Then the data were analyzed bySPSS software ver. 16, Chi- Square and Fisher’s Exact Test. In this study p-value was considered significant (P<0.05). Results: This study was performed on 158 cases (77 male and 81 female) with age ranged of 4-93 years. From those, 44 had malignant and 114 had benign lesions. The most common malignancy in this study was squamous cell carcinoma (SCC) and basal cell carcinomas (BCC), respectively. In benign lesions reactive ones, benign tumors and inflammatory lesions were more common, respectively. Conclusion: The most common lip lesions were generally benign tumors, involving the lower lip. In addition, the incidence of malignant lesions was directly related to aging. For this purpose,  in any elderly person with a lip lesion, specially squamous cell carcinoma, must first be ruled out.